Magus Tech Chapter 256: God’s blood and genetic engineering

Soon, Li Cha saw Gutas' suicide method, which was... a hunger strike.

Gutas is full of confidence in this, but Richard doesn't care.

Then...

On the first day of the hunger strike, Gutas was alive and kicking.

On the second day of the hunger strike, Gutas went on as usual.

On the third day of the hunger strike, Gutas remained unchanged.

Fourth day of hunger strike.

In the laboratory, in the main laboratory.

Gutas was firmly tied to the chair, and Li Cha drew a certain amount of blood from the opponent's arm and put it into a test tube.

Turning around, inserting a special needle into Gutas's vein. Behind the needle is a leather tube and a weird device. Behind the leather tube is a glass bottle. The glass bottle is prepared with a concentration of 0.9% saline, and 5% glucose solution.

Gutas watched Li Cha operate motionlessly, his eyes full of resentment.

Li Cha has a calm face, even with a slight smile: "To be honest, you should go on a hunger strike two days earlier. After all, compared with eating, through infusion, you only need 600ml of normal saline plus 120ml of glucose It can meet the daily needs of the human body.

Normal saline can be prepared casually, only salt and water are needed. Glucose may be a little troublesome, but it can be obtained by acid hydrolysis with some starch. No matter how you look at it, it's easier than feeding you food. Of course, it's a bit anti-human, and I didn't intend to do it in the first place, but you chose this way yourself, and I can't help it, can I?

In other words, this way of sustaining life cannot last too long, otherwise it will cause malnutrition. But it's okay, wait for a while, I can feed you liquid food by nasal feeding to supplement the nutrients that cannot be obtained by infusion. At that time, it will be more painful to insert a gastric tube, so you should be mentally prepared in advance. After all, it's all your choice, right? "

Gutas was already a little desperate in his heart, and he fully understood a truth: if he fell into the hands of Richard, he would not die!

This is... completely, no matter whether you live or die!

Shameless!

…

Many days passed in the despair of Gutas.

Laboratory, main laboratory.

Under the light of the candlelight, Li Cha quickly wrote the experimental letter with a quill pen.

"Shushasha..."

"...the experiment went well and the results were as expected..."

"...the theory obtained is slightly different from the previous one, but the direction is correct..."

"...the difficult-to-extract limit-amplification hormone was injected back into the test subject, and the test subject produced an increase similar to the third peak of the previous experiment, while the second peak and the first peak were weakened. It shows that it has negative feedback regulation phenomenon.

That is to say, the medicine prompts the body to secrete the 'limit boosting hormone', and the 'limit boosting hormone' stimulates the blood glands to secrete the 'limit boosting hormone'. While the 'limit boosting hormone' is working, it inhibits the 'promoting limit boosting hormone' and the medicine continues to work..."

"...To sum up, the secret of the blood seed and the mechanism of action of the Spartans hero potion are summarized as follows.

When ordinary people use potions: potions → regulate the human body, exert the augmentation effect, and release the 'promoting limit augmentation hormone'→terminate.

When bloodline seeds activate power: bloodline glands → secrete 'common boost hormone' → regulate the human body, exert the boost effect → terminate.

When the bloodline seed activates the power and uses the potion: potion→regulate the human body, exert the boosting effect, and release the 'promoting limit boosting hormone'→stimulate the blood vein glands→secrete the 'limit boosting hormone'→regulate the human body, exert the third peak Amplification effect, the ability to explode beyond the limit of the human body → terminate.

…”

Paused, Li Cha's eyes became serious, and he continued to write on the papyrus scroll as the experimental handbook:

"Through the above, the most valuable part of this theory is undoubtedly the use of the ultimate booster hormone. The specific mechanism of this hormone on the human body is not yet clear, but its role is completely beyond imagination. An extremely small amount can turn an ordinary person into a 'superman', and it is not an exaggeration to call it the 'blood of God'.

But how to use it is a huge problem.

First of all, the extraction is difficult, there are many links to overcome, the success rate is not high, the output rate is extremely low, the process is unstable, and the cost is high.

In addition, the source is scarce, and it must be an experimental product with bloodline seeds, which cannot be mass-produced. In fact, even small-scale production can't do it. At present, only a very small amount of laboratory tests can be satisfied, and it cannot be used in practice. "

"Hoo—"

Letting out a breath, Li Cha stopped writing and thought.

The current research on Spartans hero potion and bloodline seeds has fallen into a bottleneck. The biggest research result - "God's Blood" has been confirmed, but it cannot be used.

It's like trying to guess the lottery jackpot number, but you can't buy the lottery ticket because you lack two dollars.

How to solve it?

Li Cha rubbed his eyebrows vigorously.

How do hormones like this "blood of God" solve problems on the modern earth, and how can they be mass-produced?

In modern regions, the most representative case should be... insulin.

Well, insulin.

Insulin is a protein hormone secreted by the islet β cells in the pancreas. It is the only hormone that lowers blood sugar in the human body and is the main drug used for the treatment of diabetes.

Therefore, insulin was discovered in 1921 and was used clinically in 1922 to treat diabetes. Before insulin was discovered, diabetes was a terminal disease similar to cancer.

With the development of the times, the acceleration of urbanization and the extension of human life expectancy, the number of diabetic patients continues to increase-in a modern urban living environment, the prevalence of diabetes increases by 68% for every 10 years of age increase-therefore, the demand for insulin The number has risen linearly.

Insulin was originally extracted from animals, such as cattle, sheep, and pigs. There are certain differences in the amino acid sequence and structure of these mammalian insulin molecules, among which pig insulin is the closest to that of humans, and people obtain insulin from pigs to treat diabetes—this is the first generation of insulin.

However, porcine insulin, the first-generation insulin, differs from human insulin by 1 to 4 amino acids ~IndoMTL.com~, which is prone to immune reactions, subcutaneous fat atrophy or hyperplasia at the injection site, and insulin allergic reactions. And because of its high immunogenicity, prone to repeated hyperglycemia and hypoglycemia, insulin resistance. Most importantly, limited by the number of living pig pancreas, the yield is not very high.

After decades of research, people developed the second generation of insulin.

The second-generation insulin is a high-purity synthetic human insulin expressed by genetically engineered (recombinant DNA) yeast (brewer's yeast, Pichia or Hansenula), recombinant Chinese hamster ovary cells (CHO), etc. Its structure is the same as that of the insulin secreted by the human body itself, eliminating many defects of the first generation of insulin. And it can use tissue-cultured microorganisms or transgenic animals for large-scale production and is widely used to treat patients.

The third-generation insulin that followed was also developed on the basis of the second-generation insulin. Using genetic engineering technology to change certain structures on the insulin peptide chain, develop insulin analogues that are more suitable for human physiological needs, which can be used before meals, and are called mealtime insulin or fast-acting insulin.

Overall, to sum up, the solution to this problem on modern Earth is... genetic engineering.

"Genetic engineering." Richard said in a deep voice, thinking about everything.